Both famotidine and omeprazole can be effective drugs for treating GERD and other digestive conditions. However, the general consensus is that omeprazole is a more potent drug than famotidine. Randomized, clinical trials have shown that PPIs are more effective in treating duodenal ulcers than H2 blockers.
PPIs were found to significantly increase ulcer healing compared to H2 blockers. No significant differences were found between the PPIs that were studied, which included Prevacid lansoprazole , Protonix pantoprazole , and Aciphex rabeprazole. In people who take blood thinners, such as clopidogrel and aspirin, a PPI or H2 blocker can be used to prevent ulcers.
One systematic review found that PPIs were superior to H2 blockers in preventing gastric ulcers. The studies in the review mostly compared Prilosec omeprazole or Nexium esomeprazole with Pepcid famotidine or Zantac ranitidine.
The more effective drug is ultimately the one that works best for your condition. Sign up for Omeprazole price alerts and find out when the price changes! Most Medicare Part D plans and other insurance plans will cover generic famotidine tablets. Try the SingleCare prescription coupon card. Omeprazole delayed-release capsules are covered by most Medicare and insurance plans.
For generic omeprazole capsules, you can use a SingleCare coupon card to lower this cost. The most common side effects of famotidine and omeprazole are headache, dizziness, constipation, and diarrhea. Other gastrointestinal side effects are common and include stomach ache, nausea, and vomiting.
Omeprazole can also cause flatulence or gas. Serious side effects include allergic reactions to any of the ingredients in these medications. Allergic reactions can include rash or trouble breathing. Seek medical attention if you experience serious adverse effects. This may not be a complete list. Consult your doctor or pharmacist for possible side effects. Source: DailyMed famotidine , DailyMed omeprazole. Famotidine primarily interacts with drugs that depend on stomach acid for absorption.
These drugs include antiretrovirals, such as atazanavir and rilpivirine, and antifungals, such as ketoconazole and itraconazole. Taking famotidine can decrease the absorption of these drugs and decrease their overall effectiveness.
Ketoconazole coupons What is Ketoconazole? Itraconazole coupons What is Itraconazole? Famotidine can also interact with tizanidine, a muscle relaxer that is processed by the CYP1A2 enzyme in the liver. Famotidine can increase levels of tizanidine in the body which can lead to low blood pressure hypotension , slow heartbeat bradycardia , or extreme drowsiness.
Omeprazole also interacts with some antiretroviral medications, which can lead to a decrease in their effectiveness. These drugs may include tacrolimus and rifampin, among other drugs. Omeprazole can interact with warfarin and increase the risk of abnormal bleeding. Taking omeprazole with an immunosuppressant called methotrexate can lead to methotrexate toxicity. This may not be a complete list of all possible drug interactions. Consult a doctor with all the medications you may be taking.
Severe GERD symptoms or ulcers may be a sign of gastrointestinal cancer in some people. Famotidine should be used with caution in elderly people or those with kidney problems. However, you should consult with your healthcare provider first prior to taking these medications together. At Curist , we develop FDA-approved equivalents to big brands in order to provide the same medicine relief but at half the price of the brands. Curist products are sold online and shipped directly to your door.
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Shop All. Back to Articles Nexium vs. Prilosec vs. Pepcid vs. Esomeprazole: Which Heartburn Medicine is Better? Antacids: What is Tums Calcium Carbonate?
Prilosec vs Nexium vs Pepcid vs Tums: Frequent vs Infrequent Heartburn As an antacid, Tums can be taken up to 4 to 5 times daily as needed for 14 days. Nexium vs. Prilosec: Which Heartburn Medicine is Better? To learn more: Curist Omeprazole compare to Prilosec is available here Curist Esomeprazole compare to Nexium is available here.
Related Articles Omeprazole vs. Common Heartburn Myths and Facts. Want more? Related Articles. Heartburn Omeprazole vs. Heartburn Common Heartburn Myths and Facts. This content is for informational use only and does not replace professional medical advice, diagnosis or treatment. It is not a substitute for and should not be relied upon for specific medical recommendations.
Please talk with your doctor about any questions or concerns. Added to Cart. Frequency of gastro-oesophageal reflux disease symptoms and health-related quality of life were evaluated at baseline and after 4 weeks of treatment.
Complete relief was defined as no gastro-oesophageal reflux disease symptoms during the 7-day interval in week 4. In the famotidine group, complete relief rate in H.
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